• Mario Lozano
  • Age Progression of Mario Lozano

Real Name: Mario Alberto Lozano
Aliases: None known
Wanted For: Murder
Missing Since: 2004


Details: Mario Lozano is wanted for the murder of Isaac Guzman, 17, which occurred in Watsonville, California, on December 3, 2004. Lozano was dating Isaac's cousin Roxanne prior to the murder. When Isaac learned that Roxanne was being abused by Lozano, he confronted him. On December 3, Lozano met Isaac in front of Isaac's high school and the two got into an argument. Lozano pulled out a knife and stabbed Isaac multiple times. Tragically, Isaac Guzman passed away at a nearby hospital. Lozano fled the scene and was later charged with murder.

Isaac Guzman

Isaac Guzman

Since his disappearance, Lozano has been spotted in Mexico, Arizona, Idaho, and California. There is a $20,000 reward available in this case.
Extra Notes: The case was uploaded to the Unsolved Mysteries website on January 15, 2016. The person interviewed in the video is murder victim Isaac Guzman's aunt Sally. Lozano was profiled on both America’s Most Wanted and The Hunt with John Walsh.
Results: Captured. In February of 2018, Lozano was arrested in Mexico thanks to tips from social media. In August, he was extradited back to California to face murder charges.